Past Meetings/Webinars

Advances in Islet Transplantation as a Treatment for Diabetes πŸ—“

— Current approaches and development of stem cells for transplantation.

EMBS Chapter, IEEE Orange County Section
register
Meeting Date: October 17, 2018
Time: 6:30 PM Networking & Food; 7:00 PM Presentation
Speaker: Jonathan RT Lakey PhD, MSM, Professor of Surgery and Biomedical Engineering, UC Irvine
Location: Irvine
Cost: none
RSVP: requested, through website
Event Details: Eventbrite

Summary: Diabetes is the 4th leading cause of death in the United States. At present there is no cure for diabetes and the principal treatment is the delivery of artificial insulin guided by careful monitoring of blood glucose levels using blood-testing monitors. Despite best efforts at maintaining good blood glucose control, the health of many diabetics deteriorate in terms of advances in the secondary complications of diabetes including retinopathy, neuropathy and nephrology.

Transplantation of functional derived islet tissue, isolated from cadaveric organ donors, by the β€œEdmonton Protocol” restores euglycemia by replacing islet tissue lost to autoimmune destruction, at the expense of lifelong pharmaceutical immune suppression. These drugs have known side effects, including elevated risk of infections, lymphoma and other cancers, making the Edmonton protocol appropriate only for those diabetics with advanced life-threatening secondary complications.

Encapsulation of islets by biomaterials including alginate, derived from seaweed is viewed as the best approach to extending the Edmonton protocol to more type 1 diabetics since it would not require lifelong pharmaceutical immune suppression. The lecture will discuss current approaches in biomaterial research for protecting pancreatic islets.

The other significant issue facing islet transplantation is the source of insulin secreting cells. Advances in stem cell research have progressed so that there are recently developed protocols to convert stem cells into insulin producing cells. These stem cell derived islets could represent a significant source of cells for transplantation, however there are risks with stem cells including consistency in cell expansion protocols and the potential of differentiating into cancer or other type cells. It is key that any stem cells derived product is retrievable and is protected from immune response in an effective and carefully constructed biomaterial device. The second portion of the lecture will discuss current approaches and development of stem cells for transplantation.

Advances in both biomaterials for implantation and identifying a safe and consistent source of insulin producing cells represent key steps in islet transplantation technologies to advance our goal of finding a cure for diabetes.

Bio: Dr. Jonathan Lakey has had a long interest and research direction in cell and tissue transplantation with a focus on diabetes and islet transplantation. Dr. Lakey graduated from the University of Alberta (BSc, MSc, PhD) and received post post-doctoral training in Indianapolis and Seattle before returning to establish his research program at the University of Alberta. Dr. Lakey was also the Director of the Comprehensive Tissue Bank. He served as the Chief Scientific Officer and President for MicroIslet Inc, a public diabetes biotechnology company focused on Islet Xenotransplantation. Dr. Lakey is now the Director of Research and Associate Professor of Surgery at the University of California, Irvine. Dr. Lakey is now Director of the Clinical Islet Program at the University of California, Irvine, conducting the development of both the auto and allo islet transplant program. His contributions and partnership with Dr. James Shapiro led towards the improvement of islet isolation techniques and the development of the “Edmonton Protocol” for patients with Type 1 diabetes, a recognized major advancement in the treatment of diabetes. He has been awarded research grants and awards for diabetes and transplantation research from the Alberta Heritage Foundation for Medical Research (AHFMR), Canadian Diabetes Association and the Juvenile Diabetes Foundation International (JDFI). Dr. Lakey values the mentoring of MSc and PhD students in his research laboratory and supported training of technicians from several research and islet laboratories worldwide. He also sits on the Scientific Advisory Board for several diabetes biotechnology companies including NorMedex, Kent and DiaKine Inc., which has resulted in several industry supported research grants. Dr. Lakey has sat on several key regulatory boards establishing the safety standards for cell and tissue transplantation in Canada. Dr Lakey sits on the Biomedical Research Committee Advisory Board for One Legacy.

2018 IEEE Global Conference on Signal and Information Processing (GlobalSIP) πŸ—“

–It focuses broadly on signal and information processing with an emphasis on up-and-coming signal processing themes.

Meeting Dates: November 26 – 28, 2018

Location: Anaheim

Information and registration: www.conference.org

Summary:
It focuses broadly on signal and information processing with an emphasis on up-and-coming signal processing themes.

2018 IEEE/ACM International Conference on Computer-Aided Design (ICCAD) πŸ—“

— New challenges and innovative solutions for integrated circuit design technology and systems

Meeting Dates: November 5 – 8, 2018

Location: San Diego

Information and registration: www.conference.org
Summary:
ICCAD serves EDA and design professionals, highlighting new challenges and innovative solutions for integrated circuit design technology and systems

2018 IEEE Brain Initiative Workshop on Advanced NeuroTechnologies for BRAIN Initiatives (ANTBI) πŸ—“

— Development of novel technological innovations

Meeting Dates: November 1 – 2, 2018

Location: San Diego

Information and registration: www.conference.org
Summary:
The IEEE Brain Initiative Workshop will highlight the development of novel technological innovations, including engineered neuro-materials based implants, opto-genetics, to treat and monitor, traumatic brain injury, cognitive brain impairments, stroke and spinal cord injury etc. We also highlight translational clinical research on human-machine interface systems to significantly restore, and enhance, the impaired sensory functions and motor systems. Furthermore, global neuro-technology industry trends, nano devices, computational advances, and stem cell engineering for the treatment of neurological diseases, from the molecular to systemic levels, will be discussed.

2018 IEEE Technology Time Machine (TTM) πŸ—“

— Invited subject matter experts will share their predictions of the future.

Meeting Dates: November 1 – 2, 2018

Location: San Diego

Information and registration: www.conference.org
Summary:
Predicting, and more importantly how to get to the future is always a challenge and a desire. The IEEE rises to that challenge based upon the work it does on multiple new and emerging technologies through serving as a catalyst for developing new innovations, products and services. Invited subject matter experts will share their predictions and hot to get to that future.

2018 IEEE Green Energy and Smart Systems Conference (IGESSC) πŸ—“

— Bringing together researchers and practitioners of smart systems, sustainable and green energy technologies

Meeting Dates: October 29 -30, 2018

Location: Long Beach, California

Information and registration: www.conference.org
Summary:
The proposed conference intends to bring together researchers and practitioners from relevant fields to present and disseminate ongoing research for smart systems, sustainable and green energy technologies. This year the focus would be on Engineering a Resilient, Sustainable, Secure, Optimized Power Grid with Battery, Intelligent Systems and Smart Grid, and Transportation systems.

MILCOM 2018 – 2018 IEEE Military Communications Conference (MILCOM) πŸ—“

— Decision-makers from government, military, academia, and industry.

Meeting Dates: October 29 – 31, 2018

Location: Los Angeles, California,

Information and registration: www.conference.org
Summary:
Now in its 37th year, MILCOM attracts decision-makers from government, military, academia, and industry. The conference, being held this coming October 29-31, 2018 at the Los Angeles Airport Marriott, gathers military and government communications subject matter experts from around the globe to conduct in-depth discussions about the latest in technology advancements. MILCOM is an ideal forum for industry to demonstrate the application of these technologies and to promote products and services that provide reliable solutions to today’s mission-critical challenges.

2018 IEEE 9th International Conference on Biometrics Theory, Applications and Systems (BTAS) πŸ—“

— Experimental results for contributions in established areas such as voice, face, iris, fingerprint, and gait

Meeting Dates: October 22 – 25, 2018

Location: Redondo Beach, California

Information and registration: www.conference.org
Summary:
The 2018 IEEE 9th International Conference on Biometrics, Theory and Applications and Systems offers a broad scope, including advances in fundamental signal processing, image processing, pattern recognition, and statistical and mathematical techniques relevant to biometrics. Areas of coverage include biometrics based on voice, fingerprint, iris, periocular, face, handwriting, gait and other modalities, as well as multi-modal biometrics and new biometrics based on novel sensing technologies. Submissions will be rigorously reviewed, and should clearly make the case for a documented improvement over existing state-of-art. Experimental results for contributions in established areas such as voice, face, iris, fingerprint, and gait are encouraged to use the largest and most challenging existing publicly available datasets.